Volume 11, Issue 1 (vol- 1 2005)                   Horizon Med Sci 2005, 11(1): 48-52 | Back to browse issues page

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Abstract:   (10945 Views)
Background and Aim: Coronary heart disease (CHD) is one of the most common health problems in the world’s with high mortality and morbidity. Awareness to its risk factors is very important. There are some evidences about contribution of iron as a risk factor for CHD in recent years.Ther is few studies in this subject at the present. This study was done to determine serum ferritin and acute myocardial infarction and it's impossible role on early coronary vessels. Materials and Methods: In this cross-sectional study, 104 patients with myocardial infarction (MI),admitted to Shahid Beheshti hospital in Babol during 18 months as case group compared with 138 matched controls subjects (men 45,women 93) from regarding to serum ferritin levels.5 ml Serum were collected from each patient and ferritin level was determined by using standard biochemical and Elisa method. In last day of the second week after acute MI in the laboratory. To diagnose acute MI was based on two positive parameters such as typical chest pain,electrocardiographic changes and enzyme rising .Ferritin mean level of the two groups were compared by T and chi-square tests. Case and control group ferritin were compared in less and higher then 50 years old. Results: The mean age of patients, were 60.2312 years old and in controls were 55.72 25 years old. Mean ferritin levels in men with acute MI were 209.2178.6 g/l and in controls were 75.453.2 which was significant (P<0.0001). In the women with acute MI mean serum ferritin were 145.115.2 g/l which was meaningful compared with controls, 72.561.3 g/l (P<0.004). Conclusion: Our findings showed, the relationship between ferritin levels and MI in patients with acute MI. therefore evaluation of ferritin in patients with acute myocardial infarction is important.
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Type of Study: Original | Subject: Internal Medicine
Received: 2008/05/19 | Published: 2005/04/15

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