Volume 12, Issue 4 (vol- 4 2007)                   Horizon Med Sci 2007, 12(4): 62-66 | Back to browse issues page

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T- cell rich B- cell lymphoma . Horizon Med Sci. 2007; 12 (4) :62-66
URL: http://hms.gmu.ac.ir/article-1-110-en.html
Abstract:   (12372 Views)
TCRBCL is a rare variant of diffuse large B cell lymphoma. In the recent classification of WHO its diagnostic criteria is a T cell rich B cell lymphoma with large B cells occupying less than 10% of tumoral cell population. In all cases of T cell rich large B cell lymphoma, T lymphocytes are predominant and there are a variable number of B cells including centroblasts, polynuclear and Reed-Sternberg like cells. Thus, peripheral T cell lymphoma and lymphocyte predominant Hodgkin's disease are included in the differential diagnosis. The present study describes a 54-year-old man with TCRBCL presenting with axillary mass and striking morphological similarity with Hodgkin's lymphoma. However, further assessments led to accurate diagnosis. While lymphocyte predominant Hodgkin's lymphoma has a better prognosis, T cell rich B cell lymphoma is a high grade malignant large cell lymphoma, so applying the immunohistochemical and cytogenetic techniques is required for correct diagnosis.
     
Type of Study: Case report | Subject: Internal Medicine
Received: 2007/10/21 | Published: 2007/01/15

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