2024-03-29T17:15:29+03:30
http://imtj.gmu.ac.ir/browse.php?mag_id=57&slc_lang=en&sid=1
57-2362
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Fentanyl with Lidocaine on Hemodynamical Stability of Patients with History of Hypertension in TURP Surgery: A Double Blind Controlled Clinical Trial
M.
Saheban Maleki
dr.saheban@yahoo.com
M.
Kianmehr
A.R.
Talaei
alirezatalai@yahoo.com
M.
Moaven Saeidi Noghabi
Aims: Some severe hemodynamic changes are known as problems due to 5% lidocaine spinal anesthesia at the elderly. Such changes, also, may lead to the cardio-vascular or renal problems. The aim of this study was to compare between the hemodynamic changes in two spinal-cord anesthesia methods with 5% lidocaine (the current method) and with low 5% lidocaine dose with 50μg fentanyl in the elderly patients with a systemic blood-pressure increase history in the transurethral resection of the prostate (TURP).
Materials & Methods: In the two-blinded clinical trial, 148 patients aged more than 50 years with benign prostate hypertrophy, who had referred to 15th of Khordad Hospital of Gonabad for TURP between 2011 and 2012, were studied. The subjects, selected via simple random sampling method, were randomly divided into two groups (n=74 per group). The first and the second groups underwent spinal-cord anesthesia with the administrations of 5% lidocaine (2cc; 100mg) and 5% lidocaine (1cc; 50mg) + fentanyl (1cc; 50μg), respectively. Blood-pressure and heart-rate were recorded immediately after the anesthesia and at every 5 minutes. Data was analyzed by SPSS 21 software using independent T and Fisher’s exact tests.
Findings: Mean reductions in the systolic and the diastolic blood-pressures (p<0.001) and mean reduction in the heart-rate (p=0.009) in lidocaine+fentanyl group were significantly lower than lidocaine group. In lidocaine group, ephedrine and atropine administrations were required in 26 and 19 patients, respectively. Nevertheless, no administration either of ephedrine or of atropine was required in lidocaine + fentanyl group (p<0.001).
Conclusion: Without any hemodynamic instability, low lidocaine dose (50mg) with fentanyl (50μg) may result in sufficient anesthesia and no-pain in the elderly patients with a history of controlled high-pressure, who undergo TURP.
Spinal Anesthesia [https://www.ncbi.nlm.nih.gov/mesh/68000775]
Hemodynamics [https://www.ncbi.nlm.nih.gov/mesh/68006439]
Lidocaine [https://www.ncbi.nlm.nih.gov/mesh/68008012]
Fentanyl [https://www.ncbi.nlm.nih.gov/mesh/68005283]
2016
9
01
261
266
http://imtj.gmu.ac.ir/article-1-2362-en.pdf
10.18869/acadpub.hms.22.4.261
57-2396
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Adaptation in Response of Excitation and Inhibition Factors of Angiogenesis after 4 Weeks of Progressive Resistant Training in Sedentary Men
s.
Karami
karami.sp@gmail.com
A.R.
Ramezani
ram337@srttu.edu
Aims: The sport activity is an important factor affecting the capillary density and angiogenesis. Nitric oxide (NO) and vascular endothelial growth factor (VEGF) are the most important stimulative regulators in the angiogenesis. In addition, endostatin is one of the inhibitors of angiogenesis. The aim of this study was to investigate the adaptation in the responses of the angiogenesis inhibition and stimulating factors after 4-week increasing resistive exercises in the sedentary men.
Materials & Methods: In the semi-experimental study, 20 healthy and inactive male students, aged between 20 and 25 years, who were residents of Tehran University Dormitory, were studied in the first semester of the academic year 2015-16. The subjects, selected via available sampling method, were divided into two groups including experimental and control groups (n=10 per group). 4-week resistive exercises were done three sessions per week. Blood-sampling was done before and 48 hours after the last exercise session. VEGF, NO, and endostatin were then measured. Data was analyzed by SPSS 18 software using independent and dependent T tests, as well as Pearson correlation coefficient test.
Findings: In experimental group, VEGF and No significantly increased at the posttest stage than the pretest (p=0.001). Nevertheless, no significant difference was observed in control group (p>0.05). In both experimental and control groups, endostatin level did not significantly increase at the posttest stage than the pretest (p>0.05). In addition, VEGF and NO were the only variables that were significantly correlated (p=0.016; r=0.82).
Conclusion: 4-week increasing resistive exercises in the sedentary men significantly affect the angiogenes stimulating factors, i. e. VEGF and NO, while such exercises do not significantly affect the angiogenesis inhibition factor, i. e. endostatin.
Angiogenesis [http://www.ncbi.nlm.nih.gov/mesh/68043925]
Nitric Oxide [http://www.ncbi.nlm.nih.gov/mesh/68009569]
Resistance Training [http://www.ncbi.nlm.nih.gov/mesh/68055070]
Vascular Endothelial Growth Factor [http://www.ncbi.nlm.nih.gov/mesh/6804246
2016
9
01
267
274
http://imtj.gmu.ac.ir/article-1-2396-en.pdf
10.18869/acadpub.hms.22.4.267
57-2340
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effectiveness of group music therapy on agitatedbehaviors in elderlies with Alzheimer\'s disease
S.
Karimi
skarimi4953@gmail.com
E.
Hossieni
ebrahim.hossini@yahoo.com
GH.
Naziri
naziryy@yahoo.com
Aims: As a proper medium for the treatment interventions, music, which, as a non-invasive tool, is not expensive, can be used alongside other nursing cares. The aim of this study was to determine the effects of group music-therapy on the rate of the agitated behavior in the elderly women with Alzheimer.
Materials & Methods: In the controlled semi-experimental study with a pretest-posttest plan, 20 female patients with Alzheimer, aged between 65 and 75 years, were studied in Shiraz Islamic Azad University in 2015. The patients were residents of Farzanegan Nursing Home in Shiraz Township. The subjects, selected via available sampling method, were randomly divided into two groups including experimental (n=10) and control (n=10) groups. Data was collected using 10-question brief cognitive test questionnaire and Cohen-Mansfield agitation questionnaire. Experimental group received 4-week group music-therapy consisted of three 30- to 45-minute sessions per week. There was no intervention in control group. Data was collected in both pretest and posttest stages. Data was analyzed by SPSS 19 software using covariance analysis test.
Findings: At the pretest stage, mean rates of the agitated behaviors in experimental and control groups were not significantly different (p>0.05). Nevertheless, mean rate of the agitated behaviors in experimental group was significantly reduced at the posttest stage than both the pretest stage and control group (p<0.05). No significant difference was observed between the pretest and posttest stages in control group (p>0.05).
Conclusion: The group music-therapy is an effective tool to reduce the agitated behaviors in the elderly women with Alzheimer.
Music Therapy [https://www.ncbi.nlm.nih.gov/mesh/68009147]
Alzheimer Disease [https://www.ncbi.nlm.nih.gov/mesh/68000544]
Psychomotor Agitation [https://www.ncbi.nlm.nih.gov/mesh/68011595]
2016
9
01
275
281
http://imtj.gmu.ac.ir/article-1-2340-en.pdf
10.18869/acadpub.hms.22.4.275
57-2335
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Eight Weeks of Aerobic Training and Green Tea Supplementation on Cardiovascular Risk Factors in Inactive Overweight Women
M.
Fathei
keyvanhejazi@gmail.com
S.
Khairabadi
F.
Ramezani
K.
Hejazi
Aims: Physical activities, as well as diet, are known as the truest scientific methods to reduce the signs of the cardio-vascular diseases. The aim of this study was to investigate the effects of 8–week aerobic trainings and green tea supplementation on some of the cardio-vascular risk factors in the obese inactive women.
Materials & Methods: In the semi-experimental study, 40 obese inactive women, who were residents of Mashhad Township, were studied in 2015. The subjects, selected via purposeful available sampling method, were randomly divided into 4 groups (n=10 per group). The groups were green tea, aerobic training, aerobic training and green tea supplementation, and control groups. 8-week training program consisted of three 45- to 60-minute sessions per week. Green tea was consumed by green tea group three times a day after each meal. The composed group underwent both interventions, while control group underwent no intervention. Data was analyzed by SPSS 15 software using correlated T test and one-way ANOVA.
Findings: Mean total cholesterol level was significantly changed in green tea, aerobic training, and composed groups in the posttest stage compared to the pretest stage (p<0.05). Mean triglyceride level was significantly changed in green tea and aerobic training groups in the posttest stage compared to the pretest stage (p<0.05). Mean low density lipoprotein was significantly changed in green tea and composed groups in the posttest stage compared to the pretest stage (p<0.05). Mean high-density lipoprotein was significantly changed only in aerobic group in posttest stage compared to the pretest stage (p<0.05). In addition, mean concentration of C-reactive protein was significantly reduced in aerobic training (p=0.01) and composed (p=0.04) groups.
Conclusion: 8 weeks aerobic training, green tea consumption, and their composition reduce the cardiovascular risk factors in inactive obese women in a relatively similar manner.
Aerobic Exercise [https://www.ncbi.nlm.nih.gov/mesh/68015444]
Green Tea [https://www.ncbi.nlm.nih.gov/mesh/68013662]
Cardiovascular Abnormalities [https://www.ncbi.nlm.nih.gov/mesh/68018376]
2016
9
01
283
289
http://imtj.gmu.ac.ir/article-1-2335-en.pdf
10.18869/acadpub.hms.22.4.283
57-2370
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Moderate Intensity Aerobic Exercise on Migraine Headache Indexes and Quality of Life Improvement in Women with Migraine
Z.
Pairo
zahrapairo@gmail.com
A.H.
Parnow
parnowabdolhossein@gmail.com
P.
Sari-aslani
psariaslani@kums.ac.ir
R.
Eslami
r.eslami@gmail.com
Aims: The beneficial effects of physical activities on migraine indices, i. e. frequency, duration, and intensity of the attacks, have been proved by different studies. Despite the fact, it is required to notice the sport characteristics, such as intensity, duration, repetition, and type of the sport, to investigate the beneficial effects of the physical activities on migraine treatment. The aim of this study was to investigate the effects of the Moderate Intensity Aerobic (MIA) exercises on the migraine indices and quality of life in women with migraine.
Materials & Methods: In the controlled random semi-experimental study, 20 non-athlete women with migraine were studied in Kermanshah in 2015. The subjects were divided into two groups including control and MIA groups (n=10 per group). 8-weak MIA exercises (13-15 Borg RPE Scale) consisted of three 40-minute sessions a weak. The migraine indices of the subjects (frequency, duration, and intensity) were measured one month before and after the exercises. In addition, the quality of life and the aerobic power of the subjects were assessed 48 hours before and after the exercises. Data was analyzed by SPSS 21 software using ANCOVA, LSD post-hoc, and independent T tests.
Findings: MIA exercises resulted in significant reductions in the intensity, frequency, and duration of headache attacks, as well as an increase in the aerobic power (p<0.001). Passing from pretest to posttest, the variable change percentage was significant between control and exercise groups (p<0.05).
Conclusion: MIA exercises lead to a reduction in the migraine headache, as well as an improvement in the quality of life and aerobic readiness, in the women with migraine.
Headache [https://www.ncbi.nlm.nih.gov/mesh/68006261]
Migraine Disorders [https://www.ncbi.nlm.nih.gov/mesh/68008881]
Women [https://www.ncbi.nlm.nih.gov/mesh/68014930]
Aerobic Exercises [https://www.ncbi.nlm.nih.gov/mesh/68015444]
2016
9
01
291
297
http://imtj.gmu.ac.ir/article-1-2370-en.pdf
10.18869/acadpub.hms.22.4.291
57-2327
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of an Empowerment Program on Self-Efficacy of Epileptic Child\'s Mothers in Psychological Adaptation, Gaining Support and Receiving Information
S.
Gholami
gholamis921@mums.ac.ir
T.
Reyhani
M.
BeyraghiToosi
H.M.
Behnam Vashani
Aims: Epilepsy is one of the most prevalent childhood neurological disorders. As the primary caregivers, the mothers of epileptic children undergo different psychological pressures. The aim of the study was to investigate the effects of empowerment on the self-efficacy of the mothers of the epileptic children, concerning psychological adaptation, gaining support, and receiving information.
Materials & Methods: In the controlled two-group random clinical trial with pretest and posttest steps, 100 mothers of epileptic children hospitalized in the Neurology Ward of Ghaem Hospital of Mashhad were studied in 2014. The subjects, selected via convenience sampling method, were randomly divided into two groups including experimental (n=50) and control (n=50) groups. Data was collected using the caregiver’s self-efficacy questionnaire. Only experimental group received the empowerment program, and no intervention was conducted in control group. The mothers’ self-efficacy was measured before and after the intervention in both groups. Data was analyzed by SPSS 11.5 software using independent T, paired T, Chi-square, Fisher’s exact, and covariance tests.
Findings: The mean scores of self-efficacy, including psychological adjustment, gain a support, and receiving information, were not significantly different between the groups before the intervention (p>0.05). Nevertheless, the groups were significantly different after the intervention (p<0.001). In addition, the mean score after the intervention in experimental group was significantly higher than the score in the same group before the intervention (p<0.001).
Conclusion: The empowerment program enhances the self-efficacy of the mothers of the epileptic children in psychological adjustment, gain a support, and receiving information.
Empowerment [https://www.ncbi.nlm.nih.gov/mesh/68011209]
Self-Efficacy [https://www.ncbi.nlm.nih.gov/mesh/68020377]
Epilepsy [https://www.ncbi.nlm.nih.gov/mesh/68004827]
Psychological Adjustment [https://www.ncbi.nlm.nih.gov/mesh/2009647]
Information Lite
2016
9
01
299
306
http://imtj.gmu.ac.ir/article-1-2327-en.pdf
10.18869/acadpub.hms.22.4.299
57-2392
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Physical Activity on Serum Homocysteine Levels in Obese and Overweight Women
R.
Soori
soorirahman@yahoo.com
S.
Choopani
N.
Falahian
A.
Ramezankhani
ramezankhanizm@gmail.com
Aims: Recently, homocysteine has been noticed as the major pathogenesis factor of the cardiovascular diseases. The aim of the study was to investigate the effects of physical activities on the serum homocysteine levels, as well as other cardiovascular risk factors in either obese or overweight women.
Materials & Methods: In the controlled pretest-posttest semi-experimental study, 18 women referred to the Alzahra sport complexes in districts 3 and 4 of Tehran were studied in 2015. The subjects were selected via random sampling method and randomly divided into two groups; physical activity and control groups. And the intervention program was conducted in the former, while the latter received no intervention. The exercise protocol consisted of 10-week (5 sessions a week) stretching exercises and aerobic activities (60 to 75% of the maximum heart beat). The serum homocystein level and lipids were measured both at the start and 48 hours after the exercises. Data was analyzed by SPSS 16 software using paired T and independent T tests.
Findings: After the exercises, the mean serum homocysteine level in physical activity group significantly decreased than control group (p=0.001). Nevertheless, the difference between the lipid levels of physical activity and control groups was not significant (p>0.05).
Conclusion: Reducing the serum homocysteine concentration, 10-week physical activity might also reduce the risk factors of cardiovascular diseases in either obese or overweight women.
Homocysteine [https://www.ncbi.nlm.nih.gov/mesh/68006710]
Physical Activity [https://www.ncbi.nlm.nih.gov/mesh/68009043]
Obesity [https://www.ncbi.nlm.nih.gov/mesh/68009765]
Overweight [https://www.ncbi.nlm.nih.gov/mesh/68050177]
Women [https://www.ncbi.n
2016
9
01
307
312
http://imtj.gmu.ac.ir/article-1-2392-en.pdf
10.18869/acadpub.hms.22.4.307
57-2390
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Efficacy of Cognitive-Behavioral Stress Management Training on Symptoms Severity and Emotional Well-being of Patients with Irritable Bowel Syndrome
P.
Soleymani
p62.soleymani@gmail.com
A.
Abolghasemi
Abolghasemi1344@guilan.ac.ir
S.
vakiliabasalilu
Aref52104@yahoo.com
A.
Rahimi
Bayramzaden @yahoo.com
nasrin
Bayramzade
vakilees@gmail.com
Aims: One of the most prevalent gastrointestinal functional disorders is the irritable bowel syndrome (IBS). Different medical and psychological treatments are conducted to control the symptoms of the disease. The aim of this study was to determine the effectiveness of the cognitive-behavioral stress management training on the severity of the symptoms and emotional welfare of patients with IBS.
Materials & Methods: In the controlled pretest-posttest clinical trial study, 30 patients with IBS were studied in Ardabil in 2012. The subjects, selected via available sampling method, were randomly divided into two groups including experimental (n=15) and control (n=15) groups. Data was collected using the IBS severity questionnaire, the characteristic positive and negative affection scale, and the life satisfaction scale. Ten 90-minute group cognitive-behavioral stress management treatment sessions were conducted in experimental group. The subjects were assessed at both pretest and posttest steps. Data was analyzed by SPSS 20 software using multivariate covariance analysis test.
Findings: The mean scores of positive affection, negative affection, life satisfaction, and IBS symptom severity of experimental and control groups were significantly different at the posttest step (p<0.001). 51%, 55%, 89%, and 57% of positive affection component, negative affection component, life satisfaction, and IBS symptom severity variances could be determined by the cognitive-behavioral stress management training, respectively.
Conclusion: The cognitive-emotional stress management treatment can reduce the severity of the symptoms, while it can increase the emotional welfare, in the patients with IBS.
Stress (Psychological)[https://www.ncbi.nlm.nih.gov/mesh/68013315]
Signs and Symptoms [https://www.ncbi.nlm.nih.gov/mesh/68012816]
Emotions [https://www.ncbi.nlm.nih.gov/mesh/68004644]
Irritable Bowel Syndrome [https://www.ncbi.nlm.nih.gov/mesh/68043183]
2016
9
01
313
319
http://imtj.gmu.ac.ir/article-1-2390-en.pdf
10.18869/acadpub.hms.22.4.313
57-2382
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Motivational Interviewing on Physical Activity Intention among Obese and Overweight Women Using Protection Motivation Theory: A Randomized Clinical Trial
K.
Mirkarimi
A.R.
Charkazi
k.mirkarimi@goums.ac.ir
M.R.
Honarvar
M.J.
Kabir
R.
Berdi Ozouni- Davaji
M.
Aryaie
aryaiem2009@yahoo.com
M.
Eri
Aims: As a growing problem, obesity is one of the most important worldwide health problems. One of the major factors leading to obesity is the sedentary lifestyle. The aim of this study was to investigate the effects of motivational interviewing on the physical activity intention in the obese or overweight women, using the protection motivation theory (PMT).
Materials & Methods: In the clinical trial study, 60 obese or overweight women referred to the health centers of Gorgan were studied in 2015. The subjects, selected via non-probable and available sampling method, were randomly divided into two groups including control and motivational interviewing groups. Data was collected using a researcher-made questionnaire before the intervention and 2 and 6 months after in both groups. Data was analyzed by SPSS 18 software using independent T, Chi-square, repeated measures ANOVA, LSD, and one-variable and multivariable linear regression tests.
Findings: The scores of all the constructs of PMT in motivational interviewing group significantly increased 2 and 6 months after he intervention (p<0.001) than control group. However, the reductions in the BMI and weight anthropometric indices were not significant 2 and 6 months after the intervention (p>0.05). The most powerful constructs predicting the intention towards the physical activities 2 months after the intervention were perceived-reply efficiency, self-efficiency, and perceived intensity, successively. In addition, such factors 6 months after the intervention were attitude and perceived intensity, successively.
Conclusion: The motivational interviewing increases the scores of all the constructs of PMT, which leads to an increase in the physical activity intention in the obese or overweight women.
Motivational Interviewing [https://www.ncbi.nlm.nih.gov/mesh/68062405]
Physical Activity [https://www.ncbi.nlm.nih.gov/mesh/68009043]
Protection Motivation Theory
Overweight [https://www.ncbi.nlm.nih.gov/mesh/68050177]
2016
9
01
321
327
http://imtj.gmu.ac.ir/article-1-2382-en.pdf
10.18869/acadpub.hms.22.4.321
57-2410
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Long-Term Effect of High-Intensity Interval and Concurrent Exercise on Blood Coagulation and Fibrinolysis Parameters in Non-Athlete Healthy Young Men
V.
Sobhani
sobhani518@yahoo.com
M.
Mohammadi
rezwan_amini@yahoo.com
H.
Shirvani
shirvani.h2006@gmail.com
A.
Amini
amir.amini466@gmail.com
Aims: Following the sport activities, the blood homeostasis system, being affected by fibrinolysis and coagulation factors, is changed. The aim of this study was to investigate the effects of high-intensity interval and concurrent (aerobic-resistance) long-term sport courses on the blood fibrinolysis and coagulation parameters in healthy non-athlete young persons.
Materials & Methods: In the semi-experimental study, 30 healthy non-athlete young men were studied in Saqez in 2014. The subjects, selected via simple available sampling method, were randomly divided into three groups including concurrent (aerobic-resistance) trainings, high-intensity interval trainings, and control groups. 8-week trainings (3 times a week) were conducted in both concurrent and high-intensity interval groups. Blood sampling was done before the first session and 30 minutes after the last training session. Data was analyzed by SPSS 19 software using dependent T, one-way ANOVA, and Tukey’s post-hoc tests.
Findings: After the training intervention, the number of platelits and the fibrinogen level significantly decreased in concurrent group. In addition, prothrombin time in high-intensity interval group and the D-dimer level in both training groups significantly increased (p<0.05). The D-dimer concentrations in control and high-intensity interval groups were significantly different. In addition, the number of platelets in concurrent group was significantly different from both control and high-intensity interval groups (p<0.05).
Conclusion: 8-week high-intensity interval and concurrent trainings reduce the promoter coagulation activity in the helthy non-athlete young men, while increase the fibrinolytic activity.
Circuit-Based Exercise [https://www.ncbi.nlm.nih.gov/mesh/68065327]
Blood Coagulation [https://www.ncbi.nlm.nih.gov/mesh/68001777]
Fibrinolysis [https://www.ncbi.nlm.nih.gov/mesh/68005342]
2016
9
01
329
336
http://imtj.gmu.ac.ir/article-1-2410-en.pdf
10.18869/acadpub.hms.22.4.329
57-2413
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Hydroalcholic Extract of Curcuma longa on Adriamycin-Induced Renal Damage in Rats
R.
Mohebbati
mohebbatir@mums.ac.ir
A.A.
Abbasnezhad
abbasnezhad.abbasali@gmail.com
A.
Khajavi Rad
khajavirada@mums.ac.ir
M.
Haghshenas
Haghshenas M891@mums.ac.ir
M.R.
Khazdeir
Khazdeir MR921@mums.ac.ir
Aims: Adriamycin is one of the anti-cancer medications. Nevertheless, the medication causes renal damage. Curcuma longa has anti-inflammatory and anti-oxidant effects. The aim of this study was to determine the effects of hydroalcoholic extract of Curcuma longa on renal damage due to Adriamycin in the rat.
Materials & Methods: In the experimental study, 32 male Wistar rats were studied. Via simple random method, the rats were divided into four groups including control, Adriamycin (5mg/Kg), Curcuma longa extract (1000mg/Kg), and Curcuma longa extract with Adriamycin groups. The groups underwent 5-week treatment. 24-hour urine samples were collected at days 0, 6, 10, 14, 21, 28, and 35, to measure glomerular filtration rate. The left kidney of the animal was used to determine the renal damage percentage. Data was analyzed by SPSS 16 software using one-way ANOVA, Tukey’s post-hoc, and paired T tests.
Findings: Mean of glomerular filtration rate in Adriamycin group significantly decreased at days 21 and 35 compared to days 0 and 6. In addition, it significantly increased in Curcuma longa extract group at days 10, 14, 21, and 28 (p<0.05). The renal damage percentage significantly increased in Adriamycin (p<0.001) and Curcuma longa extract with Adriamycin (p<0.01) groups than control group. In addition, it significantly decreased in Curcuma longa extract group, as well as Curcuma longa extract with Adriamycin group, compared to Adriamycin group (p<0.001).
Conclusion: Hydroalcoholic extract of Curcuma longa reduces the renal damage percentage caused by Adriamycin in the rat, while improves glomerular filtration rate.
Curcuma longa [https://www.ncbi.nlm.nih.gov/mesh/68030024]
Renal Failures [https://www.ncbi.nlm.nih.gov/mesh/68051437]
Glomerular Filtration Rate [https://www.ncbi.nlm.nih.gov/mesh/68005919]
Adriamycin [https://www.ncbi.nlm.nih.gov/mesh/68004317]
2016
9
01
337
344
http://imtj.gmu.ac.ir/article-1-2413-en.pdf
10.18869/acadpub.hms.22.4.337
57-2477
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Hydroalcoholic Extracts of Anethum graveolens L. with Swimming Training on Lipid Profile of Diabetic Rats
M.
Askari
mahboube.askari2013@gmail.com
S.A.
Hosseini
alihoseini_57@yahoo.com
Aims: In traditional medicine, dill (Anethum graveolens) is known as the reducer of glucose, lipid and cholesterol. Physical exercises are also from the main methods of controlling and treating diabetes and hyperlipidemia. The aim of this study was to evaluate the effect of swimming exercises for 6 weeks, hydroalcoholic extracts of Anethum graveolens and their combination on lipid profile of diabetic rats.
Materials & Methods: In this experimental research, 48 Sprague Dawley male rats were randomly chosen and were divided into 4 groups (swimming training, hydroalcoholic extracts of dill, swimming exercises with hydroalcoholic extracts of dill, control), one week after induction of diabetes. Interventions were 6 weeks (5 sessions per week for 30min per session) of swimming exercises and intraperitoneal daily usage of 100mg/kg hydroalcoholic extracts of dill. After that, blood sampling was done from all samples to analyze the lipid profiles. Data was analyzed by dependent T, one way ANOVA and Tukey post hoc tests.
Findings: Using hydroalcoholic extracts of dill, swimming exercises and their combination for 6 weeks had significant effect on reduction of LDL, VLDL, TG and Cholesterol of diabetic rats (p=0.001). Swimming exercises plus extract usage had more decreasing effect on LDL (p=0.008) and cholesterol (p=0.01) than extract usage alone had. In addition, The combination treatment had more increasing effect on HDL than just extract (p=0.001) and just exercise (p=0.01) had.
Conclusion: Although 6 weeks of swimming exercises and usage of hydroalcoholic extracts of dill improves the lipid profile of diabetic rats, their combination treatment method is more effective.
Anethum graveolens [https://www.ncbi.nlm.nih.gov/mesh/68028524]
Swimming [http://www.ncbi.nlm.nih.gov/mesh/68013550]
Exercise [http://www.ncbi.nlm.nih.gov/mesh/68015444]
Diabetes Mellitus [http://www.ncbi.nlm.nih.gov/mesh/68003920]
2016
9
01
345
351
http://imtj.gmu.ac.ir/article-1-2477-en.pdf
10.18869/acadpub.hms.22.4.345
57-2423
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Comparing the Pain and Anxiety of Intravenous Access in Supine and Sitting Positions
P.
Matoury Pour
matou,rypour@yahoo.com
M.
Mahmoudi
mahmodimokhtar85@gmail.com
H.
Mafari Manesh
nurse_s.cience@yahoo.com
S.
Ebrahim Pour
eblrahim@gmail.com
F.
Rafiei
f.rafi.ei87@yahoo.com
P.
Asgari
p_ma.rjan@ymail.com
Aims: The installation of intravenous catheter is an unpleasant and painful experience for many patients. Then, it is necessary to provide new methods to either reduce or remove pain in the patients’ injection point. The aim of this study was to investigate the effects of positioning (either sitting or lying) during the installation of intravenous catheter on pain level and the following anxiety in the patients.
Instrument & Methods: In the two-blinded clinical trial study, 60 patients hospitalized in the internal wards of Arak Amir-Al-Momenin Hospital were studied in 2015. The subjects selected via available method were divided into two groups including sitting and supine groups based on the simple random allocation. The pain severity and anxiety severity indices were investigated in both groups before and after the venipuncture based on the visual analogue scale (VAS). Data was analyzed by SPSS 20 software using Chi-square, paired-T, and independent T tests.
Findings: Mean scores of anxiety before the venipuncture in both groups were not significantly different (p>0.05). Nevertheless, after the venipuncture, mean anxiety score and mean pain score in sitting group were significantly more than supine group (p=0.0001). In addition, mean scores of anxiety before and after the venipuncture in the supine group were significantly different (p=0.0001). However, no significant difference was observed between the scores before and after the venipuncture in sitting group (p>0.05).
Conclusion: During the installation of intravenous catheter, the supine position can reduce the pain level and the following anxiety in the patients compared to the sitting position.
Anxiety [https://www.ncbi.nlm.nih.gov/mesh/68001007]
Pain [https://www.ncbi.nlm.nih.gov/mesh/68010146]
Supine Position [https://www.ncbi.nlm.nih.gov/mesh/68016683]
Injections
Intravenous [https://www.ncbi.nlm.nih.gov/mesh/68007275]
2016
9
01
353
358
http://imtj.gmu.ac.ir/article-1-2423-en.pdf
10.18869/acadpub.hms.22.4.353
57-2186
2024-03-29
10.1002
Internal Medicine Today
Intern Med Today
2981-0086
2981-0086
10.18869/acadpub.hms
2016
22
4
Effect of Acupressure of Xue Hai Point on Severity of Pain in Primary Dysmenorrhea
H.
Ezadi
ezadi.hamide@yahoo.com
M.
Geranmay
geranmay@tums.ac.ir
N.S.
Taebi
Nasim_st@yahoo.com
Aims: There is a prevalence of dysmenorrhea in women. The treatment of the disease includes medication and non-medication treatments. The non-medication treatments, such as acupressure, are recently noticed by the patients. The aim of this study was to investigate the effects of pressure on the tenth spleen point on the pain severity in the primary dysmenorrhea.
Materials & Methods: In this one-blind random clinical trial, 100 female students with primary dysmenorrhea, who were residents of the dormitories of Tehran University of Medical Sciences, were studied in 2012. The subjects, selected via purposeful sampling method, were divided into control (n=50) and intervention (n=50) groups based on the randomization program. Data was collected by a demographic questionnaire, the pain ruler, and the visual scale. The pressure medicine and its application, the tenth spleen point, way to find the point, and its massage method were trained in intervention group. There was no intervention in control group. The pain severity was measured before the intervention and one, two, and three months after it. Data was analyzed by SPSS 16 software using Chi-square and independent T tests.
Findings: There was no significant difference between control and intervention groups in mean pain severity (p=0.143). Therefore, the groups were the same in the pain severity. There were significant differences in the first, the second, and the third months after the intervention between the groups. In addition, there was a reduction in pain severity after 3 months in intervention group (p<0.001).
Conclusion: Pressure on the tenth spleen point is effective on the reduction of pain severity in the primary dysmenorrhea.
Dysmenorrhea [http://www.ncbi.nlm.nih.gov/mesh/68004412]
Acupressure [http://www.ncbi.nlm.nih.gov/mesh/68019050]
Tenth Spleen (Xue Hai) Point
2016
9
01
359
363
http://imtj.gmu.ac.ir/article-1-2186-en.pdf
10.18869/acadpub.hms.22.4.359