@ARTICLE{Maroufi, author = {Pourlak, Tala and Halimi, Monireh and Pourlak, Tannaz and Maroufi, Parham and Ghaderpour, Saber and Shokoohi, Arefeh and }, title = {Effect of Extracts of Cloves (Syzygium Aromaticum) on Hepatic Cell Damage and Oxidative Stress Caused by Diabetes in Adult Rats}, volume = {26}, number = {4}, abstract ={Aims: In this study, we investigated the effect of clove extract (Syzygium aromaticum) on liver cell damage and oxidative stress caused by diabetes in adult rats. Methods & Materials: For this study, 28 female rats were collected and divided into four groups: A: Control group; B: Diabetic Control group (DC) which received 20% glycerol dissolved in normal saline as carriers; C: Diabetic rats (DSA) treated with cloves hydroalcoholic extract (4 mg/kg); d) diabetic rats (DG) treated with glibenclamide (5 mg/kg) as a standard drug. Findings: The fasting blood sugar and serum triglyceride levels in the DC group increased significantly compared to the control group (P<0.05). In DC, DG, and DSA groups, high-density lipoprotein, and serum insulin levels decreased significantly compared to the control group (P<0.05). Also, in DG and DSA groups, high-density lipoprotein and serum insulin levels increased significantly compared to the DC group. Conclusion: Cloves can affect fasting blood sugar, serum insulin levels, serum fat profile levels, and prevent liver tissue damage in diabetic rats caused by streptozotocin. }, URL = {http://imtj.gmu.ac.ir/article-1-3534-en.html}, eprint = {http://imtj.gmu.ac.ir/article-1-3534-en.pdf}, journal = {Internal Medicine Today}, doi = {10.32598/hms.26.4.3400.1}, year = {2020} }