RT - Journal Article T1 - Toxicity Effects of Intraperitoneal Injection of Biochemical Nanosilver on Cardiac Tissue Structure Following Aerobic Training in Male Wistar Rats JF - QHMS YR - 2019 JO - QHMS VO - 25 IS - 3 UR - http://imtj.gmu.ac.ir/article-1-3147-en.html SP - 172 EP - 183 K1 - Exercise K1 - Silver nanoparticles K1 - Toxicity K1 - Heart tissue K1 - Rats AB - Aims Silver nanoparticles are among the most valuable products of nanoscale technology, widely used in various sciences. The present study investigated the effects of biochemical silver nanoparticles on the structure of the heart tissue of non-observatory rats in the course of aerobic training. Methods & Materials In this experimental study, 30 male Wistar rats aged 8 to 12 weeks and weighing 34.9±202 g were studied. The rats were randomly divided into 6 groups of control, aerobic training, aerobic training, and nanobiological injection, aerobic and-nanochemical injection, nanobiological injection, and nanochemical injection. Chemical and biological silver was injected intraperitoneally after a period of aerobic training. The specimens were discarded after 48 hours, and the heart tissue was removed. Findings The obtained results revealed the tissue changes, including irregularities and the convergence of chemical nanosilver group significantly increased, compared to the controls. Additionally, in the biological group, there was a slight dispersion of blood in some areas. Following the aerobic training and injection of toxic nanosilver, there was no irregularities, detachment, and hypertension. Only in some areas, sporadically, the accumulation of blood cells was observed in the aerobic training and nanochemical groups. Conclusion More tissue damage occurred in chemical silver nanoparticles, than the biological nanoparticle. Possibly, aerobic training can be highly predictive of these effects. LA eng UL http://imtj.gmu.ac.ir/article-1-3147-en.html M3 10.32598/hms.25.3.172 ER -