@ARTICLE{Hosseini, author = {Hosseini, S.A. and Nemati, J and Ranjbar, M and Edalatmanesh, M.A. and Zar, A. and }, title = {Hypoglycemic Interactive Effects of Ginger Eextract and Eendurance Training in Diabetic Rats}, volume = {23}, number = {4}, abstract ={Aims: Diabetes is a metabolic disorder that results in hyperglycemia due to non-regulation of blood glucose. The aim of this study was to evaluate the hypoglycemic interactive effects of Ginger extract and endurance training in diabetic rats. Materials & Methods: In this experimental study, 40 streptozotocin-induced diabetic rats were randomly divided into four groups (control, endurance training, Ginger extract and endurance training with Ginger extract). The training groups ran 8 to 16 meters per minute for four weeks, five sessions per week, and each session for 30 minutes on treadmill. Ginger extract groups received daily 100 mg/kg Ginger extract intraperitoneal for four weeks. At the end, levels of fasting glucose, insulin and insulin resistance were measured. Data were analyzed by SPSS 21 software using dependent T-test, one way ANOVA and Tukey's post hoc test. Findings: Levels of fasting glucose, insulin and insulin resistance in endurance training group, Ginger extract group and endurance training with Ginger extract group were significantly lower than control group. Also, levels of fasting glucose, insulin and insulin resistance in endurance training with Ginger extract group were significantly lower than endurance training group and Ginger extract group (p<0.01). Conclusion: Endurance training with use of Ginger extract has hypoglycemic interactive effects on improving glucose indices in diabetic rats, leading to a decrease in levels of fasting glucose, insulin and insulin resistance in streptozotocin-induced diabetic rats. }, URL = {http://imtj.gmu.ac.ir/article-1-2627-en.html}, eprint = {http://imtj.gmu.ac.ir/article-1-2627-en.pdf}, journal = {Internal Medicine Today}, doi = {}, year = {2017} }