TY - JOUR JF - QHMS JO - Intern Med Today VL - 22 IS - 3 PY - 2016 Y1 - 2016/6/01 TI - Effect of 6 Weeks of High-Intensity Interval Training with Cinnamon Supplementation on Serum Apelin Concentration and Insulin Resistance in Overweight Boys TT - اثر 6 هفته تمرین تناوبی شدید و مکمل دارچین بر غلظت سرمی آپلین و مقاومت به انسولین پسران دارای اضافه وزن N2 - Aims: Playing an important role in regulating glucose hemostasis, apelin might empower the correlation between any increase in the adipose tissue mass and obesity and the correlated metabolic diseases. The aim of this study was to investigate the effects of 6-week intensive periodic massive exercises with cinnamon supplementation on the apelin serum concentration and insulin resistance in the overweight boys. Materials & Methods: In the semi-experimental study, 40 male overweight students were studied in Zahedan in 2014. The samples, randomly selected, were divided into four groups including exercise, exercise and supplementation, supplementation, and control. 6-week intensive periodic massive exercises were done in the exercise groups. In addition, three 380mg-cinnamon capsules were administrated in the supplementation groups. Blood sampling was done from the subjects 48 hours before and after the exercise program. Apelin, glucose, and insulin levels were measured. Data was analyzed by SPSS 19 software using one-way and two-way ANOVA tests and covariance analysis. Findings: There were significant differences between “exercise” and “exercise and supplementation” groups and “control” group in apelin and insulin resistance levels after the exercise program (p=0.0001). In addition, there was a significant difference between “cinnamon supplementation” and “control” groups in insulin resistance (p=0.001).There were significant differences between the exercise groups and supplementation group in apelin (p=0.0001) and insulin resistance (p=0.003) levels. Conclusion: The serum apelin level and the insulin resistance index in the overweight boys are reduced by 6-week intense periodic massive exercises. In addition, the cinnamon supplementation only reduces the insulin resistance index. SP - 177 EP - 183 AU - Kazemi, A. AU - Rahmati, M. AU - Akhondi, M. AD - Physical Education Department, Literature & Humanities Faculty, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran KW - Insulin Resistance [http://www.ncbi.nlm.nih.gov/mesh/68007333] KW - Overweight [http://www.ncbi.nlm.nih.gov/mesh/68050177] KW - Apelin [http://www.ncbi.nlm.nih.gov/mesh/67115436] KW - Cinnamomum zeylanicum [http://www.ncbi.nlm.nih.gov/mesh/68002935] UR - http://imtj.gmu.ac.ir/article-1-2281-en.html DO - 10.18869/acadpub.hms.22.3.177 ER -