%0 Journal Article %A Jalaeian Taghaddomi, R. %A Sharifian, A. %A Jalili-e-Shahri, MR. %T Premedication with intranasal midazolam in children undergoing probing of nasolacrimal duct and its effect on recovery and discharge time %J Internal Medicine Today %V 11 %N 2 %U http://imtj.gmu.ac.ir/article-1-216-en.html %R %D 2005 %K Premedication; Intranasal midazolam; Probing of nasolacrimal duct; Recovery, %X Background and Aim: The perfect preanesthetic medication and its ideal route of administration are still debated, but for pediatric surgical patients undergoing brief procedures, preanesthetic medication is frequently omitted because of the concern that it will prolong the children recovery from anesthesia. In this study, the effects of nasally administered midazilam on anesthetic recovery and hospital discharge time were determined in children undergoing probing of the nasolacrimal duct. Materials and Methods: Using a randomized, double- blind, placebo- controlled design, 60 ambulatory surgical patients between 12-22 months of age undergoing probing on nasolacrimal duct were entered into the study. One group received 0.3 mg/kg intranasal midazolam, a second group received intranasal saline drop (0.06 ml/kg). All patients were anesthetized with N2O, oxygen and halothane (1.5-2%). The duration of anesthesia lasted between 6-12 minutes. After preanesthetic medication, the children were evaluated for ease of separation and induction of anesthesia. In addition, the time from when the anesthetic was discontinued until the child recovered from anesthesia and the time the child was discharged home were recorded by a nurse observer blinded to the patient grouping. Results: Children receiving midazolam had smoother, calmer parent- child separation and anesthesia induction scores, and their anesthesia recovery times and hospital discharge times were the same as those receiving placebo. Conclusion: For children undergoing brief surgical procedure nasal midazolam provides satisfactory anxiolysis without delaying anesthesia recovery and hospital discharge. %> http://imtj.gmu.ac.ir/article-1-216-en.doc %P 22-25 %& 22 %! %9 Original %L A-10-1-88 %+ %G eng %@ 2981-0086 %[ 2005