TY - JOUR JF - QHMS JO - Intern Med Today VL - 12 IS - 1 PY - 2006 Y1 - 2006/4/01 TI - Clinical and laboratory evaluation in 17 cases of macroprolactinemia identified by polyethylene glycol precipitation test TT - بررسی کلینیکی و آزمایشگاهی هفده مورد مبتلا به ماکروپرولاکتینمی تشخیص داده شده با آزمون رسوبی پلی‌اتیلن گلیکول N2 - Abstract Background and Aim: Macroprolactinemia in which most circulating PRL forms Big Big PRL (>150KD), is a major causes of Idiopathic Hyperprolactinemia with mild or lack of symptoms. We aimed in this study to introduce a simple and inexpensive polyethylene Glycol precipitation test (PEG)for macroprolactin evaluation and avoiding other expensive diagnostic investigations also evaluation of classic hyperprolactinemia symptoms in macroprolactinemic patients Materials and Methods: In this descriptive study, serum prolactin was measured before and after precipitation of macroprolactin by polyethylene glycole in 90 patients with hyperprolactinemia (PRL>30µg/L), furthermore clinical and radiographic findings recorded. Results: 18.8% of cases were macroprolactinemic without hyperprolactinemic classic symptom. Conclusion: Regarding to high prevalence of macroprolactinemia and lack of classic symptoms of hyperprolactinemia and to avoid diagnostic and trapeutic pitfalls the screening for macroprolactin in all hyperprolactinmia recommended. SP - 5 EP - 10 AU - Tayebi-Meybodi, N. AU - Amooeian, S. AU - Farzadnia, M. AU - Memar, B. AU - Mahmoudi, M. AU - Mozouni, M. AU - Erfanian, Z. AD - KW - Hyperprolactinemia; Macroprolactin; Polyethylenglycol UR - http://imtj.gmu.ac.ir/article-1-50-en.html ER -