logo
Volume 15, Issue 2 (Vol.15-3 2009)                   Intern Med Today 2009, 15(2): 11-16 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kamkar A. The study of antioxidant activity of essential oil and extract of Iranian Anethum graveloens. Intern Med Today 2009; 15 (2) :11-16
URL: http://imtj.gmu.ac.ir/article-1-592-en.html
, akamkar@ut.ac.ir
Abstract:   (11346 Views)
Background and Aim: Today we know well that radicals cause molecular transformations and gene mutations in many types of organisms. Oxidative stress is well- known to cause many diseases, and scientists in many different disciplines became more interested in natural sources which could provide active compounds to prevent or reduce its impacts on cells. Antioxidants, which can inhibit or delay the oxidation of an oxidizable substrate in a chain reaction, therefore, appear to be very important in the prevention of many diseases. The number of antioxidant compounds synthesized by plants as secondary products. This study was designed to evaluate antioxidant activity of the essential oil and ethanolic extract of Iranian Anethum graveloens. Materials and Methods: In this research antioxidant activities of the samples were determined by two different test systems namely 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and ß-carotene/linoleic acid assays. Results: The essential oil of Anethum graveloens and their extract were able to reduce the stable free radical DPPH with an IC50 of 41000, 340 μg/mL and in ß-carotene/linoleic acid assay, exhibiting 32% and 56% inhibition at 2 g/m L , respectively. These parameters in BHT were 5 μg/mL and 95%, respectively. Conclusion: In conclusion, the antioxidant activity of ethanolic extract of Anethum graveolens was significantly higher than that of essential oil (p<0.05), which was due to difference in their phenolic content. A high correlation was found between the antioxidant activity and total phenolic content.
Full-Text [PDF 297 kb]   (10619 Downloads)    
Type of Study: Original | Subject: Internal Medicine
Received: 2009/10/10 | Published: 2009/07/15

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.