Abstract Insulinoma are the most common islet cell tumors and located almost exclusively in the pancreas. Most of these tumors are sporadic, they may also be associated with the multiple endocrine neoplasia type 1 syndrome (MEN1). More than 90% of insulinomas are benign. Preoperative radiographic localization may prove difficult. Intraoperative palpation and ultrasound remain the gold standard for detection. A 27 years male presented with history of intermitent fainting attacks, headache ,loss of consciousness and increased body weight. his fasting blood sugar was 40 mg/dl and insulin glucose ratio was 0.57-0.76. CT Scan of abdomen did not show tumour in pancreas.Laparotomy was done and tomour in head of pancras was removed .according to clinical and microscopic finding The tamour was found to be a insulinoma.. the aim of this study is recognition of this rare tumor and diagnosis with laboratory methods.

Keywords: Pancreas; Endocrine tumours; Insulinoma; Hypoglycemia

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