Volume 14, Issue 3 (Vol-3 2008)                   Horizon Med Sci 2008, 14(3): 64-71 | Back to browse issues page

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Mazloom Z, Moosavi Sh.F Z, Shabbidar S, Aghasadeghi K, Rajae F A. The impact of vitamin E on glycemic control and lipid profiles in type 2 diabetes patients. Horizon Med Sci. 2008; 14 (3) :64-71
URL: http://hms.gmu.ac.ir/article-1-436-en.html
1- , zohreh.mazloum@gmail.com
Abstract:   (15669 Views)
Background and Aim: Diabetic complications have been related to hyperlipidemia and hyperglycemia. Alpha –tochoferol has antioxidant effects and can improve lipid profiles. We evaluated the effect of vitamin E supplementation on glucose, insulin and lipid profiles in type 2 diabetic patients. Materials and Methods: In a randomized clinical trial, 31 patients included 14 men and 17 women (51.9±5.9 year) with type 2 diabetes were randomly divided into treatment with vitamin E (800 mg/day) and placebo groups for 2 months. Plasma glucose, Insulin and lipid profiles were measured at the beginning and at the end of 3 months supplementation. The paired and independent t-test was used for analyzing of data. Results: Anthropometric indexes were stable throughout the study. Vitamin E administration lowered fasting plasma insulin concentrations (28.25±2.37 and 27.8±2.56, p<0.016) plasma triglyceride concentration (279.41±194.99 and 212.48±85.18 p <0.03). The plasma glucose and the other lipid profiles did not change after vitamin E consumption for 2 months. Conclusion: We need more research to establish beneficial effect of vitamin E intake in type 2 diabetic patients.
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Type of Study: Original | Subject: Internal Medicine
Received: 2009/03/2 | Published: 2008/10/15

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