Volume 23, Issue 4 (Fall 2017)                   Horizon Med Sci 2017, 23(4): 257-263 | Back to browse issues page

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Khademi Y, Azarbayjani M, Hosseini H. Simultaneous Effect of High-Intensity Interval Training (HIIT) and Consumption of Flaxseed on Serum Levels of TNF-α and IL1β in Rats. Horizon Med Sci. 2017; 23 (4) :257-263
URL: http://hms.gmu.ac.ir/article-1-2636-en.html
1- Physical Education Department, Physical Education Faculty, Central Tehran Branch, Islamic Azad University, Tehran, Iran , youneskhademi3@gmail.com
2- Sport Physiology Department, Physical Education Faculty, Central Tehran Branch, Islamic Azad University, Tehran, Iran
3- Sport Physiology Department, Human Science Faculty, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Abstract:   (1839 Views)
Aims: The high concentration of Interleukin-1 beta (IL-1β) and Tumor Necrosis Factor- α (TNF-α) is an important risk factor for developing cardiovascular disease. The purpose of this study was to investigate the simultaneous effect of High-Intensity Interval Training (HIIT) and the use of flaxseed oil with different doses on the serum levels of TNF-α and IL1β in rats.
Materials & Methods: In this experimental study, 30 Wistar rats were randomly divided into six groups: control, training, 10mg/kg supplement, 30mg/kg supplement, training with 10mg/kg supplement and training with 30mg/kg supplement. The groups performed High-Intensity Interval Training (HIIT) for 10 weeks and received flaxseed oil extracts. Data were analyzed by one way ANOVA and LSD post hoc test.
Findings: Serum levels of IL1β in the training group and training groups with doses of 10 and 30mg/kg of extract were significantly lower than the control group. Serum levels of IL1β in the training group with 30mg/kg of extract, was significantly lower than group with 10mg/kg of extract. Also, serum levels of TNF-α in the training group, training groups with doses of 10 and 30mg/kg of extract and group with 30mg/kg of extract were significantly lower than the control group. Serum levels of TNF-α in the training group with 30mg/kg of extract were significantly lower than other groups (p<0.05).
Conclusion: High-Intensity Interval Training (HIIT) and consumption of flaxseed oil for 10 weeks
have interactive effects on reduction of serum levels of TNF-α and IL-1β in rats.
 
 
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Type of Study: Original | Subject: Physiology
Received: 2016/11/9 | Accepted: 2017/03/13 | Published: 2017/09/26

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