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:: Volume 23, Issue 4 (Fall 2017) ::
Horizon Med Sci 2017, 23(4): 325-330 Back to browse issues page
Hypoglycemic Interactive Effects of Ginger Eextract and Eendurance Training in Diabetic Rats
S.A. Hosseini 1, J Nemati 2, M Ranjbar 3, M.A. Edalatmanesh , A. Zar 4
1- Sport Physiology Department, Human Science Faculty, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran , alihoseini_57@yahoo.com
2- Physical Education Department, Educational Science & Psychology Faculty, Shiraz University, Shiraz, Iran
3- Sport Physiology Department, Human Science Faculty, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
4- Physical Education & Sport Science Department, Literature & Humane Science Faculty, Jahrom University, Jahrom, Iran
Abstract:   (781 Views)
Aims: Diabetes is a metabolic disorder that results in hyperglycemia due to non-regulation of blood glucose. The aim of this study was to evaluate the hypoglycemic interactive effects of Ginger extract and endurance training in diabetic rats.
Materials & Methods: In this experimental study, 40 streptozotocin-induced diabetic rats were randomly divided into four groups (control, endurance training, Ginger extract and endurance training with Ginger extract). The training groups ran 8 to 16 meters per minute for four weeks, five sessions per week, and each session for 30 minutes on treadmill. Ginger extract groups received daily 100 mg/kg Ginger extract intraperitoneal for four weeks. At the end, levels of fasting glucose, insulin and insulin resistance were measured. Data were analyzed by SPSS 21 software using dependent T-test, one way ANOVA and Tukey's post hoc test.
Findings: Levels of fasting glucose, insulin and insulin resistance in endurance training group, Ginger extract group and endurance training with Ginger extract group were significantly lower than control group. Also, levels of fasting glucose, insulin and insulin resistance in endurance training with Ginger extract group were significantly lower than endurance training group and Ginger extract group (p<0.01).
Conclusion: Endurance training with use of Ginger extract has hypoglycemic interactive effects on improving glucose indices in diabetic rats, leading to a decrease in levels of fasting glucose, insulin and insulin resistance in streptozotocin-induced diabetic rats.
 
Keywords: Exercise Training [https://www.ncbi.nlm.nih.gov/mesh/68015444], Ginger [https://www.ncbi.nlm.nih.gov/mesh/68020939], Blood Glucose [https://www.ncbi.nlm.nih.gov/mesh/68001786], Diabetes Mellitus [https://www.ncbi.nlm.nih.gov/mesh/68003920]
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Type of Study: Original | Subject: Physiology
Received: 2016/10/24 | Accepted: 2017/04/12 | Published: 2017/09/26
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Hosseini S, Nemati J, Ranjbar M, Edalatmanesh M, Zar A. Hypoglycemic Interactive Effects of Ginger Eextract and Eendurance Training in Diabetic Rats. Horizon Med Sci . 2017; 23 (4) :325-330
URL: http://hms.gmu.ac.ir/article-1-2627-en.html


Volume 23, Issue 4 (Fall 2017) Back to browse issues page
مجله علمی پژوهشی افق دانش The Horizon of Medical Sciences
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