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Abstract Background and Aim: The epidemic of HIV/AIDS is a well-recognized global phenomenon and the most serious of infectious disease challenges to public health. The number of people living with HIV (PLWH) has increased in all Asian regions, including Iran. It can damage all physical, social, spiritual, psychological and financial aspects of human function. The present research was designed and conducted to better understand the interactions of people living with HIV/AIDS. Materials and Methods: This qualitative study was conducted using an interpretative phenomenological approach. In-depth, audio-taped and semi-structured interviews with 19 participants were used to collect data. Questions were open-ended and largely discovery-oriented. Interviews were audio-taped and transcriptions were analyzed to highlight the participants’ life experiences. Observations were also recorded in comprehensive field notes. A hermeneutic approach was used to analyze the data. Results: According to the findings, 19 participants were between 21 and 56 years of age 24.1% single, 47.4% had CD4 counts under 200 cells/mm3 and others with earlier phase of HIV infection. Four main themes emerged: (a) beliefs (b) supportive tent, (c) different behaviors and (d) mutual reactions, including some sub-themes. Conclusions: Other people's behaviors are understood differently for PLWH in such a way that some behaviors are threatening. Other negative behaviors in some aspects have been accepted and most of them have had negative impacts on their reactions. Therefore, people with HIV/AIDS diagnosis face many challenges. Improving the level of awareness and others' attitudes and strengthening appropriate interaction are suggested.

Keywords: Experience, interaction, HIV/AIDS, phenomenology

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