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:: Volume 21, Number 1 (Spring 2015) ::
Horizon Med Sci 2015, 21(1): 53-58 Back to browse issues page
Comparing the Impact of Prescribing One Dose or Two Doses of Injecting Betamethasone for Pregnant Women on Preterm Infants Outcomes
Fereshte Saymari1, Farnaz Zan vakili 2, Masoome Rezaie1, Majid Mansori3, Abdolrahim Afkhamzadeh53
1- MD Obstetrics & Gynecology Department, Medicine Faculty, Kurdistan University of Medical Sciences, Sanandaj, Iran
2- MD Obstetrics & Gynecology Department, Medicine Faculty, Kurdistan University of Medical Sciences, Sanandaj, Iran , Dr.fzandvakili@gmail.com
3- MD Family & Social Medicine Department, Medicine Faculty, Kurdistan University of Medical Sciences, Sanandaj, Iran
Abstract:   (1234 Views)

Aims: The use of corticosteroids and abandoning the delivery are of preventive actions of newborns’ respiratory distress syndrome. The aim of this clinical trial was to compare the effect of one versus two doses of Betamethasone on the outcomes of preterm infants. Materials & Methods: In this quasi-experimental clinical trial, 100 preterm labor pregnant women who referred to Sanandaj Be’sat Hospital in 2013 were selected by purposive sampling method and were divided into one dose (12mg Betamethasone) and two doses (12mg Betamethasone with the interval of 24 hours) groups. Information about delivery and gender, weight and Apgar scores of newborn were recorded in the checklist. Newborns were examined for infant respiratory distress syndrome, necrotizing enterocolitis, cerebral hemorrhage and neonatal death. Data were analyzed in SPSS 20 software by Chi-square and Mann-Whitney U tests. Findings: 14 newborns (28%) in one dose and 13 (24.5%) in two doses group had respiratory distress syndrome (p=0.689). 4 newborns (8%) in one dose and 7 (13.2%) in two doses group had enterocolitis and 8 newborns (16%) in one dose and 9 (17%) in two doses group needed respiratory support (p>0.05). Conclusion: Single-dose or two doses administration of Betamethasone in preterm mothers have no impact on newborn after birth.

Keywords: Betamethasone [http://www.ncbi.nlm.nih.gov/mesh/68001623]Infant, Premature [http://www.ncbi.nlm.nih.gov/mesh/68007234]Respiratory Distress Syndrome, Newborn[http://www.ncbi.nlm.nih.gov/mesh/?term=D012127]
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Type of Study: Original | Subject: Obstetrics and Gynecology
Received: 2014/12/15 | Accepted: 2015/03/17 | Published: 2015/03/17
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DOI: 10.18869/acadpub.hms.21.1.53


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Saymari F, Zan vakili F, Rezaie M, Mansori M, Afkhamzadeh5 A. Comparing the Impact of Prescribing One Dose or Two Doses of Injecting Betamethasone for Pregnant Women on Preterm Infants Outcomes. Horizon Med Sci . 2015; 21 (1) :53-58
URL: http://hms.gmu.ac.ir/article-1-2112-en.html
Volume 21, Number 1 (Spring 2015) Back to browse issues page
مجله علمی پژوهشی افق دانش The Horizon of Medical Sciences
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