Aims: Self-controling and non-drug intervention methods such as aerobic activities and diet programs have a significant impact on insulin resistance and quality of life in type II diabetic patients. The purpose of this research was to investigate the effect of 12 weeks of aerobic training with diet on insulin resistance and quality of life in type II diabetic patients.

Materials & Methods: In this quasi-experimental research in 2013-14, obese female with type II diabetes in Taybad City, Iran, were selected by achievable sampling method and were divided into aerobic training (n=12) and aerobic training with diet (n=11) groups. Aerobic training in both groups was performed in 36 sessions of exercise training 3 sessions per week with an intensity of 50-70% heart rate reserve. In addition to aerobic training, the second group participated in diet that included 500kcal of energy less than the estimated daily energy requirement. Data were analyzed with SPSS 16 software by paired and independent T tests.

Findings: The levels of blood glucose, insulin and insulin resistance reduced significantly just in aerobic training with diet group (p<0.05) just the fasting blood sugar difference was significant between 2 groups (p=0.035). Also, there were significant differences between groups in subscales of role limitations due to physical health problems (p=0.001), role limitations due to emotional problems (p=0.002), social functioning (p=0.002), pain (p=0.001) and general health (p=0.002).

Conclusion: 12 weeks of aerobic training with diet lead to improvement in blood sugar, fasting insulin, insulin resistance and some subscales of quality of life in type II diabetic patients.