Abstract

  Background and Aim: One of the most common causes of post operative morbidity is nausea and vomiting which are followed by aspiration pneumonia, dehydration, patients' delayed discharge, or electrolyte and acid-base imbalances. Even though different protocols have been reported for the prevention of nausea and vomiting, it has still remained as one of the post operative problems.

  Materials and Methods : In this study, we evaluated the effects of two medications (Ondansetron and the combination of Dexametasone-Metocholopromide) on prevention of the post operative nausea and vomiting. They were prescribed with a specific dosage, half an hour prior to the patients' appendectomy procedure. The patients were evaluated 24 and 48 hours after the operation in the recovery room for any related signs and symptoms.

  Results: The Ondansetron effect on reducing the patient's nausea and vomiting has been about 30 % more than the effect of Dexametasone-metocholopromide combination.

  Conclusion: As no specific complication has been reported for Ondansetron, its favorable effects on decreasing of post operative nausea and vomiting, cost-effectiveness, and easily availability, it may be recommended to be used as an effective medication for prevention of post operative nausea and vomiting.